Primary Research Publications

2016

Panciera T, Azzolin L, Fujimura A, Di Biagio D, Frasson C, Bresolin S, Soligo S, Basso G, Bicciato S, Rosato A, Cordenonsi M, Piccolo S. Induction of Exandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ. Cell Stem Cell. 2016 Sep 9. pii: S1934-5909(16)30256-9. doi: 10.1016/j.stem.2016.08.009.



2016

Zanconato F, Cordenonsi M, Piccolo S. YAP/TAZ at the Roots of Cancer. Cancer Cell 29, 783-803.



2016

Zanconato F, Battilana G, Cordenonsi M, Piccolo S. YAP/TAZ as therapeutic targets in cancer. Curr Opin Pharmacol. 29, 26-33.



2016

Nowell CS, Odermatt PD, Azzolin L, Hohnel S, Wagner EF, Fantner GE, Lutolf MP, Barrandon Y, Piccolo S, Radtke F. Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction. Nat Cell Biol. 18, 168-80.



2015

Zanconato F, Forcato M, Battilana G, Azzolin L, Quaranta E, Bodega B, Rosato A, Bicciato S, Cordenonsi M, Piccolo S. Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. Nat Cell Biol.17, 1218-27.



2014

Piccolo S, Twists of fate. Sci Am. 311, 74-81.



2014

Piccolo S, Dupont S, Cordenonsi M. The biology of YAP/TAZ: hippo signaling and beyond. Physiol Rev. 94, 1287-312.



2014

Sorrentino G, Ruggeri N, Specchia V, Cordenonsi M, Mano M, Dupont S, Manfrin A, Ingallina E, Sommaggio R, Piazza S, Rosato A, Piccolo S, Del Sal G. Metabolic control of YAP and TAZ by the mevalonate pathway. Nat Cell Biol. 16, 357-66.



2014   Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S, Frasson C, Basso G, Guzzardo V, Fassina A, Cordenonsi M, Piccolo S. YAP/TAZ incorporation in the -catenin destruction complex orchestrates the Wnt response. Cell 1, 157-70.
     
2013   Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N, Dupont S, Piccolo S. A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell 5, 1047-59.
     
2012  
Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Cordenonsi M, and Piccolo S (2012) Role of TAZ in Wnt signaling. Cell 7, 1443-56
     
2012   Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S. Self-regulation of the head-inducing properties of the Spemann organizer. Proc Natl Acad Sci U S A. 18 38, 15354-9
     
2012  
Halder G, Dupont S, and Piccolo S (2012) Transduction of mechanical and cytoskeletal cues by Yap and TAZ. Nature Reviews in Molecular and Cell Biology 9, 591-600
     
2012  
Montagner M, Enzo E, Forcato M, Zanconato F, Parenti A, Rampazzo E, Basso G, Leo G, Rosato A, Bicciato S, Cordenonsi M and Piccolo S (2012). Sharp1 suppresses breast cancer metastasis by promoting degradation of HIFs/hypoxia-inducible factors. Nature 487, 380-4
     
2011  
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M., Parenti A, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, and Piccolo S (2011). The Hippo Transducer TAZ Confers Cancer Stem Cell-related Traits on Breast Cancer Cells. Cell 147, 759-72
     
2011  
Inui M, Manfrin A, Mamidi A, Martello G, Morsut L, Soligo S, Enzo E, Moro S, Polo S, Dupont S, Cordenonsi M, and Piccolo S (2011). USP15 is a deubiquitylating enzyme for receptor-activated SMADs. Nat Cell Biol. 13, 1368-75
     
2011  
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Zanconato F, Le Digabel J, Forcato M, Elvassore N and Piccolo S (2011). Role of YAP/TAZ in mechanotransduction. Nature 474: 179-183
     
2010  
Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, Enzo E, Guzzardo V, Rondina M, Spruce T, Parenti AR, Daidone MG, Bicciato S and Piccolo S (2010) A microRNA targeting Dicer for metastasis control. Cell 141, 1195-1207
     
2010  
Morsut L, Enzo E, Aragona M, Soligo S, Dupont S, Bressan G, Chambon P, Losson R, and Piccolo S (2010). Negative control of Smad activity by Ectodermin/Tif1g patterns the mammalian embryo. Development 137, 2571-2578
     
2010  
Inui M, Martello G and Piccolo S. (2010). microRNA control of signal transduction. Nature Reviews in Molecular Cell Biology 11, 252-63
     
2009  
Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, Solari A, Parenti R, Rosato A, Bicciato S, Balmain A and Piccolo S. (2009) A mutant-p53/Smad complex opposes p63 to empower TGF-beta induced metastasis. Cell 137, 8798
     
2009  
Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M, Martello M, Stinchfield MJ, Soligo S, Morsut L, Inui M, Moro S, Modena M, Argenton F, Newfield S and Piccolo S. (2009) FAM/USP9x, a deubiquitinating enzyme essential for TGF-beta signaling controls Smad4 monoubiquitination. Cell 136, 123-135
     
2007  
Martello G, Zacchigna L, Inui M, Montagner M, Adorno M, Mamidi A, Morsut L, Soligo S, Tran U, Dupont S, Cordenonsi M, Wessely O and Piccolo S. (2007) MicroRNA control of Nodal signalling. Nature 449:183-8
     
2007  
Cordenonsi M, Montagner M, Adorno M, Zacchigna L, Martello G, Mamidi A, Soligo S, Dupont S, and Piccolo S. (2007). Integration of TGF- and Ras/MAPK signaling through p53 phosphorylation. Science 315:840-3.
     
2006  
Zacchigna, L.1, Vecchione, C., Notte, A., Cordenonsi1, M., Dupont1, S., Maretto1, S., Cifelli, G., Ferrari, A., Maffei, A., Fabbro, C., Braghetta, P., Marino, G., Selvetella, G., Aretini, A., Colonnese, C., Bettarini, U., Russo, G., Soligo, S., Adorno, M., Bonaldo, P., Volpin, D., Piccolo#, S., Lembo, G., and G. M. Bressan# (2006). Emilin1, a cysteine-rich glycoprotein of elastic fibers, is required for blood pressure homeostasis by regulating TGF-? maturation (2006). Cell 124, 929-42 # corresponding author, 1 SP lab
     
2005  
Dupont, S., Zacchigna, L., Cordenonsi, M., Soligo, S., Adorno, M., Rugge, M., and Piccolo, S. (2005). Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. Cell 121, 87-99.
     
2003  
Cordenonsi, M., Dupont, S., Maretto, S., Insinga, A., Imbriano, C., and Piccolo, S. (2003). Links between tumor suppressors: p53 is required for TGF- gene responses by cooperating with Smads. Cell 113, 301-314.
     
2003  
Maretto, S., Cordenonsi, M., Dupont, S., Braghetta, P., Broccoli, V., Hassan, A. B., Volpin, D., Bressan, G. M., and Piccolo, S. (2003). Mapping Wnt/-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A 100, 3299-3304.


To see all the publications, click here.