PUBLICATIONS
|
ALL PUBLICATIONS |
|
Prof. Ildikò Szabò: Google Scholar - PubMed Prof. Luigi Leanza: Google Scholar - PubMed Dr. Vanessa Checchetto: Google Scholar - PubMed |
| SELECTED PUBLICATIONS | |
| Capera J, Pérez-Verdaguer M,
Peruzzo R, Navarro-Pérez M, Martínez-Pinna J, Alberola-Die A,
Morales A, Leanza L, Szabó I, Felipe A. A novel mitochondrial Kv1.3-caveolin axis controls cell survival and apoptosis. Elife. 2021 |
PubMed Full text link |
| Szabo I, Zoratti M, Biasutto L.
Targeting mitochondrial ion channels for cancer therapy. Redox Biol. 2021 |
PubMed Full text link |
| Checchetto V, Leanza L, De
Stefani D, Rizzuto R, Gulbins E, Szabo I. Mitochondrial K+ channels and their implications for disease mechanisms. Pharmacol Ther. 2021 |
PubMed Full text link |
| Peruzzo R, Corrà S, Costa R,
Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D,
Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R,
Szabò I. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction. Nat Commun. 2021 |
PubMed Full text link |
| Rossin F, Costa R, Bordi M,
D'Eletto M, Occhigrossi L, Farrace MG, Barlev N, Ciccosanti F,
Muccioli S, Chieregato L, Szabo I, Fimia GM, Piacentini M, Leanza L.
Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates. Cell Death Dis. 2021 |
PubMed Full text link |
| Bachmann M, Rossa A, Antoniazzi
G, Biasutto L, Carrer A, Campagnaro M, Leanza L, Gonczi M, Csernoch
L, Paradisi C, Mattarei A, Zoratti M, Szabo I. Synthesis and cellular effects of a mitochondria-targeted inhibitor of the two-pore potassium channel TASK-3. Pharmacol Res. 2021 |
PubMed Full text link |
| Costa R, Muccioli S, Brillo V,
Bachmann M, Szabò I, Leanza L. Mitochondrial dysfunction interferes with neural crest specification through the FoxD3 transcription factor. Pharmacol Res. 2021 |
PubMed Full text link |
| Peruzzo R, Mattarei A, Azzolini
M, Becker-Flegler KA, Romio M, Rigoni G, Carrer A, Biasutto L,
Parrasia S, Kadow S, Managò A, Urbani A, Rossa A, Semenzato G,
Soriano ME, Trentin L, Ahmad S, Edwards M, Gulbins E, Paradisi C,
Zoratti M, Leanza L, Szabò I. Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family. Redox Biol. 2020 |
PubMed Full text link |
| Costa R, Peruzzo R, Bachmann M,
Montà GD, Vicario M, Santinon G, Mattarei A, Moro E,
Quintana-Cabrera R, Scorrano L, Zeviani M, Vallese F, Zoratti M,
Paradisi C, Argenton F, Brini M, Calì T, Dupont S, Szabò I, Leanza
L. Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction. Cell Rep. 2019 |
PubMed Full text link |
| Urbani A, Giorgio V, Carrer A,
Franchin C, Arrigoni G, Jiko C, Abe K, Maeda S, Shinzawa-Itoh K,
Bogers JFM, McMillan DGG, Gerle C, Szabò I, Bernardi P. Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore. Nat Commun. 2019 |
PubMed Full text link |
| Paggio A, Checchetto V, Campo
A, Menabò R, Di Marco G, Di Lisa F, Szabo I, Rizzuto R, De Stefani
D. Identification of an ATP-sensitive potassium channel in mitochondria. Nature. 2019 |
PubMed Full text link |
| Teardo E, Carraretto L,
Moscatiello R, Cortese E, Vicario M, Festa M, Maso L, De Bortoli S,
Calì T, Vothknecht UC, Formentin E, Cendron L, Navazio L, Szabo I.
A chloroplast-localized mitochondrial calcium uniporter transduces osmotic stress in Arabidopsis. Nat Plants. 2019 |
PubMed Full text link |
| Leanza L, Romio M, Becker KA,
Azzolini M, Trentin L, Managò A, Venturini E, Zaccagnino A, Mattarei
A, Carraretto L, Urbani A, Kadow S, Biasutto L, Martini V, Severin
F, Peruzzo R, Trimarco V, Egberts JH, Hauser C, Visentin A,
Semenzato G, Kalthoff H, Zoratti M, Gulbins E, Paradisi C, Szabo I.
Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo. Cancer Cell. 2017 |
PubMed Full text link |
| Szabo I, Zoratti M. Mitochondrial channels: ion fluxes and more. Physiol Rev. 2014 |
PubMed Full text link |
| Carraretto L, Formentin E,
Teardo E, Checchetto V, Tomizioli M, Morosinotto T, Giacometti GM,
Finazzi G, Szabó I. A thylakoid-located two-pore K+ channel controls photosynthetic light utilization in plants. Science. 2013 |
PubMed Full text link |
| Checchetto V, Segalla A,
Allorent G, La Rocca N, Leanza L, Giacometti GM, Uozumi N, Finazzi
G, Bergantino E, Szabò I. Thylakoid potassium channel is required for efficient photosynthesis in cyanobacteria. Proc Natl Acad Sci U S A. 2012 |
PubMed Full text link |
| Leanza L, Henry B, Sassi N,
Zoratti M, Chandy KG, Gulbins E, Szabò I. Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells. EMBO Mol Med. 2012 |
PubMed Full text link |
| De Stefani D, Raffaello A,
Teardo E, Szabò I, Rizzuto R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature. 2011 |
PubMed Full text link |
| Szabò I, Lepple-Wienhues A,
Kaba KN, Zoratti M, Gulbins E, Lang F. Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes. Proc Natl Acad Sci U S A. 1998 |
PubMed Full text link |
| Zoratti M, Szabò I. The mitochondrial permeability transition. Biochim Biophys Acta. 1995 |
PubMed Full text link |